Formula Ingredient Deck
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Benefits Of Each Ingredient
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Vitamin A
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- Supports vision health, skin health, immune health, and increases antioxidant support (182, 183).
- Supports antioxidant function via decreased inflammatory cytokines (inflammation), decreased reactive oxygen species, and increased L-glutathione production (master antioxidant) (182, 183).
- Supports visual health via increased amounts of plasma vitamin A in macular (eye) tissues (182,183).
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Vitamin B1
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- Supports aerobic energy metabolism (oxidative phosphorylation), cell growth, optimal neuronal conduction (nerve impulses), and cardiovascular health (94).
- Supports cardiovascular function and aids as a neuroprotective agent in individuals with vitamin B-1 deficiencies (94, 95).
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Vitamin B2
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- Supports conversion and activation of other B vitamins, red blood cell production and serves as a cofactor for both glucose and fat metabolism (energy production) (92,93).
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Vitamin B3 (Niacin)
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- Major B vitamin that supports cardiovascular health by inhibiting hepatic(liver) triglyceride synthesis, reducing very low-density lipoprotein (VLDL) secretion, and increasing HDL plasma concentrations (9).
- Reduces conversion of VLDL into LDL proteins and serum lipoprotein concentrations in plasma (blood) (9).
- Vital for regulation of gene expression, cell cycle progression, and DNA repair, and cell death (9).
- Supports healthy inflammatory response via antioxidant and anti-apoptotic (prevention of cell death) properties (9).
- Prevents pathologies(diseases) such as Pellagra and reduces prevalence of nervous anorexia, cancer, and crohn's disease (10, 11).
- Supports sensitization of tumors to radiation via apoptosis (cell death) cascade of tumor mass and improves oxygen delivery to malignant tissues (cancer cells) (12).
- Supports cognitive health by reducing age-related decline of NAD+, increasing quinolinic acid and reducing neuroinflammation (9).
- Increased niacin associated NAD+ levels have been shown to increase neurotransmission, learning and memory (9).
- Niacin reduces the prevalence of neurodegenerative pathologies by preventing mitochondrial dysfunction (9).
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Vitamin B6
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- Serves as a cofactor in more than 150 enzymatic reactions associated in blood sugar regulation, immunity, cardiovascular function, neuronal health, metabolic, and digestive health (38, 40).
- Reduces plasma glucose (blood sugar levels) via by inhibiting the activity of small-intestinal α-glucosidases (enzymes associated with glucose metabolism) (39).
- Functions as an antioxidant by counteracting the formation of reactive oxygen species (inflammatory markers) and advanced glycation end-products (38,40).
- May support blood sugar regulation in women with gestational diabetes (40).
- Cofactor for enzymes involved in DNA metabolism (40).
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Biotin
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- Supports conversion of food into cellular energy, hair health, skin health, and cognitive function (213,214).
- Enhances glucose breakdown into skeletal muscle tissue (213,214).
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Vitamin B12
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- Supports proper DNA synthesis, folate cycle function, energy production, cognitive function, and immune health (51,53).
- Aids as an antioxidant via direct scavenging of reactive oxygen species (inflammation), preserving l-glutathione levels (master antioxidant), and reducing oxidative stress (51).
- May prevent vitamin b-12 deficiency diseases such as anemia, neurodegenerative disease, cardiovascular disease, and osteoporosis (53).
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Vitamin C
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- Supports immune, cardiovascular, skin, cognitive, fat burning, and digestive health (97, 98).
- Supports immune health via increased oxidant, free radical scavenging, and fueling neutrophilic (immune cell) activity in chemotaxis, phagocytosis, and microbial killing (97,98).
- Supports fat burning by increasing carnitine biosynthesis (molecule required for mitochondrial fatty acid oxidation) (97,98).
- Supports accelerate bone healing after a fracture, increase type I collagen synthesis, and reduce oxidative stress (inflammation) (98).
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Vitamin E
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- Supports immune function, cognitive health, cardiovascular health, and bone health (204,205,206,207,208)
- Supports immune health via neutralizing free radicals and reactive oxygen species, and increased T lymphocyte-mediated immune function (204).
- Supports cardiovascular health via reduced cholesterol (204).
- Supports cognitive function via reduced oxidative stress, inflammation, and DNA damage of neuronal tissues (208).
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Vitamin D3
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- Supports exercise performance, immune health, muscle growth, optimal bone health, hormonal health, immune function, increased sexual health, cardiovascular health, glucose tolerance, strength, and positive mood (77,78,79).
- Supports hormonal health via high amounts of vitamin D receptor (VDR) activity in hormone based negative feedback loop reactions (77,78).
- Supports cardiovascular health via improved absorption of calcium, reduced atherosclerotic activity, stimulating cardiomyocytes, and improved vascular health (77,78).
- Supports exercise performance via reduced exercise associated inflammation and muscle damage (77,78).
- Supports sexual health via increased activity of Vitamin D receptor activity of testosterone production (79)
- Supports immune function via decreases of inflammatory cytokines and aiding immune cells (77,78).
- Supports joint health via regulating calcium and phosphorus and bone remodeling along with other calcium-regulating actions (77,78).
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Calcium
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- Supports bone health, muscle function, and cardiovascular health (36,37).
- Regulates processes of bone resorption, mineralization, and fracture repair (36,37).
- Increases the effect of physical exercise on bone mineral acquisition in the period preceding puberty (36,37).
- Prevents the development of preeclampsia (36,37).
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Magnesium
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- Supports optimal nerve function, muscle contractions, cardiovascular, bone health, and decreased anxiety (90,91).
- Supports biological reactions such as ATP fueled reactions and pancreatic insulin secretion (90,91).
- Supports reduction systolic blood pressure, fasting glucose, triglycerides, and healthy HDL levels (90,91).
- Reduces peripheral cortisol levels in the central nervous system and supports relaxation and decreased anxiety (90,91).
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Zinc
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- Supports immune function, skin health, cognitive function, and vision (172,173).
- Supports stimulation of the innate and adaptive immune system (172,173).
- Supports the activation of lymphocytes and activation of innate and T cell mediated immunity (172,173).
- Supports cognitive function by modulation of neuronal signaling in areas of the brain associated with memory and learning (hippocampus) (172,173).
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Bilberry
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- Supports vision health, cardiovascular function, increased nitric oxide production, blood sugar regulation, and antioxidant support (167,168).
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Lycopene
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- Supports prostate health, cardiovascular support, antioxidant, anti-inflammatory, and chemoprotective properties against cancer (191,192, 193).
- Combats inflammation via scavenging of free radicals and reduced oxidative damage of DNA. (191,192,193).
- Combats carcinogenesis via carcinogen-metabolizing enzymes, apoptosis (cancer cell death), anti-proliferation, pro-differentiation, and anti-lipid peroxidation activities. (193).
- Inhibits phosphorylation of anti-oncogenes such as p53 and Rb. It also inhibits G0/G1 and S-phase of the cell cycle (193).
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Lutein
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- Carotenoid that supports vision health, immune health, cardiovascular health, and combats diabetic retinopathy (155,156).
- Supports increased lutein concentration in the macula and exhibits various features such as anti-inflammatory, anti-oxidative, and blue light-filtering effects (155,156).
- Supports visual health via increased lutein concentration in the macular layer of retina, reduced susceptibility to age related macular disease, reduced prevalence of cataracts, and improved plasma level of lutein and retinal macular pigment level (155,156).
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Potassium
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- Supports reduced blood pressure in hypertensive patients and improves hydration in individuals with low potassium levels (262).
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Co Q10
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- Supports cardiovascular health, cellular energy production, and antioxidant support (88).
- Supports the prevention of peroxidative damage to cell membranes and reduced oxidative damage to blood vessels (88).
- Protects DNA associated oxidative damage and stabilizes cells to combat inflammation (89).
- Enhances blood flow via increased endothelial function and improved cardiac output in patients with cardiovascular disease (89).
- Supports energy production (bioenergetic pathways) via increased ATP (energy currency of the body) production in the mitochondrial respiratory chain (89).
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Lactobacillus Acidophilus
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- Supports athletic performance, enhanced gut microbiome, increased muscle mass, immune health, reduced cortisol levels, digestive health, cognitive function, and improved allergy symptoms (103,104, 107, 108, 109).
- Supports 70% of gut-immunological axis (gut immune system) via enhanced mucosal immune response (toll-like receptors), and upregulation of genetic markers associated with macrophage (gut-immune cell) activity (108, 109).
- Supports digestive and immune health via decreased irritable bowel symptoms, suppression of helicobacter pylori growth (pathogenic bacteria), reduced histamine (reduced allergic response), and reduced gut inflammation (103,104, 107, 108, 109).
- Supports athletic performance via reduction of respiratory tract infections, reduced muscle damage, improved body composition, reduction lactate induced exercise (muscle burn), and body composition (108).
- Supports gut-brain axis via increased neural, endocrine (hormonal), and anti-inflammatory modulation of the hypothalamic-pituitary-adrenal (HPA) axis (108)
- Reduces inflammation via activation of Toll-like receptors (TLRs) and downregulates the expression of nuclear factor (NF)-κB and pro-inflammatory cytokines (inflammation markers) (109).
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Cranberry
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- Supports cardiovascular health, immune health, and may combat against urinary tract infections (156, 157).
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Grapefruit
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- Supports increased nitric oxide production, reduces blood pressure, reduces DNA damage, increases collagen production, increases bone strength, and aids as a neuroprotective agent (31).
- Supports antioxidant function via modulation of antioxidant enzyme expression, protection against oxidative damage, and reduced reactive oxygen species (31).
- Supports cardiovascular health via reduced atherosclerosis, inhibiting lipid peroxidation, and improved endothelial vascular function (31).
- Supports immune, cardiovascular, skin, cognitive, fat burning, and digestive health (97, 98).
- Supports immune health via increased oxidant, free radical scavenging, and fueling neutrophilic (immune cell) activity in chemotaxis, phagocytosis, and microbial killing (97,98).
- Supports fat burning by increasing carnitine biosynthesis (molecule required for mitochondrial fatty acid oxidation) (97,98).
- Supports accelerate bone healing after a fracture, increase type I collagen synthesis, and reduce oxidative stress (inflammation) (98).
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L-Cysteine
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- Supports natural collagen production.
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L-Lysine
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- Supports skin health, immune health, antioxidant function, reduced anxiety, and energy production (313).
- Supports reduced anxiety via decreases in plasma cortisol concentrations (313).
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L-Methionine
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- Reduces inflammation and increases energy production via increased creatine synthesis (112).
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Quercetin
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- Supports antioxidant, anti-inflammatory, immune system defense, reduced homocysteine (allergies), reduced triglycerides and combats bacterial infections (114,115,116).
- Supports immune health via reduced c-reactive protein (major inflammatory biomarker), increased neutrophil chemotaxis, macrophage phagocytosis, NK cell lytic activity and mitogen-stimulated lymphocyte (white blood cell) proliferation (114).
- Supports antiviral and antibacterial activity in influenza A strains H1N1 (114).
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